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Article

Causal relationship between immune cells and myocardial infarction: A Mendelian randomization study.

Medicine - 12 Sept 2025

Xu Yinyin, Yang Jing, Xue Rong, Zhang Guojiang, Zhang Yanhua

Abstract excerpt

Myocardial infarction (MI) is a major cause of death worldwide. It is been suspected for a long time that MI is linked to immune cells. However, observational studies are plagued by confounding factors and reverse causality, whether the immune response is a cause or consequence of MI remains unknown. The present study aimed to determine whether genetically immune cells might have a causal effect on MI. According...

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Genome-Wide Association Study
Mendelian Randomization Analysis
Myocardial Infarction
Polymorphism, Single Nucleotide

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40958290
DOI: 10.1097/MD.0000000000043682
PMCID: PMC12440469

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