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Whole genome analysis reveals chromosomal and plasmid-mediated convergence of drug resistance in Klebsiella pneumoniae isolates.

Antonie van Leeuwenhoek - 15 Jul 2026

Irusan Dhinakaran, Dangari Akshay Sadanand, Shetty Varsha Prakash, Karunasagar Iddya, Deekshit Vijaya Kumar, Karunasagar Anusha

Abstract excerpt

The emergence of antimicrobial resistance (AMR) in Klebsiella pneumoniae poses a significant threat to public health. This study aims to elucidate the mechanisms of colistin and fluoroquinolone resistance using whole-genome sequencing in two K. pneumoniae isolates. Two clinical isolates of K. pneumoniae that phenotypically showed resistance to colistin and ciprofloxacin but did not yield any corresponding drug...

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Share to Chromosomes, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42458139
DOI: 10.1007/s10482-026-02381-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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