Ferritin and Liver Steatosis in Children: Interactions Between Metabolic Clustering and PNPLA3 Variants.

doi:10.3390/ijms27073044

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Article

Ferritin and Liver Steatosis in Children: Interactions Between Metabolic Clustering and PNPLA3 Variants.

International journal of molecular sciences - 27 Mar 2026

Podeanu Mihaela-Andreea, Sandu Raluca Elena, Vintilescu Bianca Ștefănița, Ionele Claudiu Marinel, Rogoveanu Ion, Streață Ioana, Niculescu Carmen Elena, Florescu Dan Nicolae, Cazacu Sergiu-Marian, Andrei Ștefania Cornelia, Barbu Adina Maria, Stepan Mioara Desdemona

Abstract excerpt

Metabolic abnormalities are frequently associated with hepatic steatosis and low-grade inflammation, yet the contributions of iron metabolism and genetic susceptibility are not fully understood. We aimed to investigate the relationship between serum ferritin, hepatic steatosis, metabolic risk clustering, and the PNPLA3 rs738409 gene variant in children. A total of 68 children aged 6-14 years underwent...

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PMID: 41977232
DOI: 10.3390/ijms27073044
PMCID: PMC13073952

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PNPLA3

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