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Article

Mendelian Randomization Studies of Major Depressive Disorder, Schizophrenia, Bipolar Disorder, and Cancers: A PRISMA Review and Meta-Analysis.

Endocrine, metabolic & immune disorders drug targets - 1 Jan 2026

Vitale Elsa, Maistrello Lorenza, Rizzo Alessandro, Santoni Matteo, Motamed-Jahromi Mohadeseh, Sallustio Alessandra, Tramacere Francesco

Abstract excerpt

INTRODUCTION: Previous literature has reported ambiguous results regarding the association of severe psychiatric disorders and an increasing risk of cancer disease. The aim of our analysis was to explore any associations between severe psychiatric disorder (SPD), like schizophrenia (SCZ), Bipolar Disorder (BD) and recurrent major depression (MDD), and cancer diseases by meta- analyzing Mendelian Randomization...

Read the complete abstract on PubMed

Topics

Humans
Bipolar Disorder
Schizophrenia
Mendelian Randomization Analysis
Major Depressive Disorder

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Neoplasms

Risk Factors

Genetic Predisposition to Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 41968701
DOI: 10.2174/0118715303432589260216095347
PMCID: PMC13595330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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