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Article

LHX2 is associated with tumor microenvironment characteristics in clear cell renal cell carcinoma and modulates the malignant phenotypes of cancer cells.

Pathology, research and practice - 1 Jun 2026

Wang Tengda, Peng Qiang, Li Shuaijie, Yang Liming

Abstract excerpt

BACKGROUND: LIM-homeobox gene 2 (LHX2) participates in the progression of various tumors. However, its expression pattern, clinical significance, relationship with tumor microenvironment (TME), and biological function in clear cell renal cell carcinoma (ccRCC) remain unclear. METHODS: The expression, prognostic value, clinical association and effects on immune cell infiltration of LHX2 in ccRCC were analyzed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41962205
DOI: 10.1016/j.prp.2026.156450

Genes

LHX2
JAK2
STAT3
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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