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Article

Function of NEK2 in clear cell renal cell carcinoma and its effect on the tumor microenvironment.

Medicine - 17 May 2024

Tang Peng, Zheng Gangfu, Xu Congcong, Yu Nengfeng, Du Jiaqi, Hu Liqian, Zhou Zhan, Zheng Yichun

Abstract excerpt

BACKGROUND: Previous studies have revealed the critical functions of NEK2 in controlling the cell cycle which is linked to poor prognosis in multiple tumor types, but less research has been devoted to clear cell renal cell carcinoma (ccRCC). METHODS: We downloaded clinical data from the gene expression omnibus (GEO) and TCGA databases together with transcriptional and mutational datasets. Strongly coexpressed...

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Source

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Identifiers

PMID: 38758909
DOI: 10.1097/MD.0000000000037939
PMCID: PMC11098263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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