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Prognostic and therapeutic implications of extracellular matrix associated gene signature in renal clear cell carcinoma

7 Apr 2021

Abstract excerpt

Complex interactions in tumor microenvironment between ECM (extra-cellular matrix) and cancer cell plays a central role in the generation of tumor supportive microenvironment. In this study, the expression of ECM-related genes was explored for prognostic and immunological implication in clear cell renal clear cell carcinoma (ccRCC). Out of 964 ECM genes, higher expression (z-score > 2) of 35 genes showed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33828127
DOI: 10.1038/s41598-021-86888-7

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