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Article

Tumor microenvironment immune subtypes for classification of novel clear cell renal cell carcinoma profiles with prognostic and therapeutic implications.

Medicine - 19 Mar 2021

Wang Qiang, Hu Jinding, Kang Weiting, Wang Jin, Xiang Yuzhu, Fu Min, Gao Hui, Huang Zhilong

Abstract excerpt

ABSTRACT: Currently, no effective prognostic model of clear cell renal cell carcinoma (ccRCC) based on immune cell infiltration has been developed. Recent studies have identified 6 immune groups (IS) in 33 solid tumors. We aimed to characterize the expression pattern of IS in ccRCC and evaluate the potential in predicting patient prognosis. The clinical information, immune subgroup, somatic mutation, copy number...

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Identifiers

PMID: 33725966
DOI: 10.1097/MD.0000000000024949
PMCID: PMC7982168

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