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Article

Molecular characteristics and clinical outcomes of patients with gastroesophageal cancer diagnosed at ages younger than 50 years.

JNCI cancer spectrum - 9 May 2026

Storandt Michael H, Teslow Emily A, Yu Yingying, Yilma Binyam, Mahipal Amit, Jin Zhaohui

Abstract excerpt

BACKGROUND: The incidence of gastroesophageal cancer diagnosed at ages younger than 50 years is increasing. Assessment of the clinicopathologic and molecular characteristics of these cancers is limited currently. METHODS: This analysis used Tempus' clinicogenomic database to compare patients diagnosed with gastroesophageal cancer at ages younger than 50 vs 50 years and older who completed tumor molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41950398
DOI: 10.1093/jncics/pkag034
PMCID: PMC13158797

Genes

CDH1
TP53
CDKN2A
ERBB2
KRAS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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