A new SNP comparison (SnpC) method for detecting unique/enriched gene-SNP variants and comparing population gene mutation diversity.

Abstract excerpt

BACKGROUND: Comparing mutation patterns and population-specific genetic signatures, such as single-nucleotide polymorphisms (SNPs), is of fundamental importance in genetic and genomic studies today. The problem is challenging because it falls into the category of NP-hard problems, meaning that the computational time increases exponentially, or even faster, as the problem size grows. Additionally, existing...

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