Association of CLOCK rs1801260 Polymorphism with Sleep Quality in Residents of the Far North.

doi:10.1007/s10517-026-06637-6

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Article

Association of CLOCK rs1801260 Polymorphism with Sleep Quality in Residents of the Far North.

Bulletin of experimental biology and medicine - 1 Jan 2026

Gubin D G, Kolomeychuk S N, Borisenkov M F, Petrov I M, Markov A A, Petrova Yu A, Voronin K A, Mezhakova M S, Boldyreva Yu V, Markov V A, Shigabaeva A U

Abstract excerpt

In a longitudinal study of permanent Arctic residents, an actigraphic analysis of sleep quality indicators across different seasons revealed no significant overall seasonal differences in sleep efficiency (p = 0.487). However, TT homozygotes for the CLOCK gene rs1801260 polymorphism the exhibited lower sleep efficiency, particularly in spring and summer. Multiple linear regression, incorporating categorical...

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PMID: 41942665
DOI: 10.1007/s10517-026-06637-6

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CLOCK

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