Article
Molecular and Phenotypic Characterization of Fluid-Derived Patient-Derived Cell and Organoid Models in Advanced Gastric Cancer.
Journal of gastric cancer - 1 Apr 2026
Moon Ye Jin, Kwon Woo Sun, Park Chan Hee, Jang Jinsoo, Park Juin, Yoon Byeong Gyu, Mun Han Byeol, Kim Namju, Lee Choong-Kun, Jeung Hei Cheul, Shin Su-Jin, Kim Tae Soo, Rha Sun Young
Abstract excerpt
PURPOSE: Patient-derived cells (PDCs) and patient-derived organoids (PDOs) are complementary preclinical models widely used in translational cancer research. However, their molecular and functional differences have not been systematically characterized. This study established and analyzed paired PDC and PDO models derived from the same gastric cancer ascites to delineate platform-dependent molecular and...
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