Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrated analysis uncovers KCMF1 genetic susceptibility and the SNRPD2 axis in renal cell carcinoma.

International journal of medical sciences - 1 Jan 2026

Pao Jiunn-Bey, Hsueh Yu-Mei, Chen Pei-Ling, Huang Tzu-Hao, Li Chia-Yang, Geng Jiun-Hung, Lu Te-Ling, Huang Chao-Yuan, Huang Shu-Pin, Bao Bo-Ying

Abstract excerpt

The ZZ-type zinc-finger family has emerged as an important regulator of tumorigenesis; however, its roles in renal cell carcinoma (RCC) susceptibility and prognosis are largely unexplored. This study aimed to systematically evaluate the genetic variants within this gene family to identify novel risk drivers and elucidate their downstream pathogenic networks. A total of 148 single-nucleotide polymorphisms (SNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Renal Cell

Share to Gene Expression Regulation, Neoplastic

Share to Kidney Neoplasms

Share to Polymorphism, Single Nucleotide

Share to Prognosis

Share to Taiwan

Source

Open in PubMed Open full text

Identifiers

PMID: 41938511
DOI: 10.7150/ijms.129880
PMCID: PMC13048855

Genes

KCMF1
SNRPD2
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrated analysis uncovers KCMF1 genetic susceptibility and the SNRPD2 axis in renal cell carcinoma.PMID 41938511Read ↗

Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumorSemantic proximity Read ↗

SNP-mediated lncRNA-ENTPD3-AS1 upregulation suppresses renal cell carcinoma via miR-155/HIF-1α signaling.Semantic proximity Read ↗

A pan-cancer analysis of the oncogenic role of zinc finger protein 419 in human cancerSemantic proximity Read ↗

Genetic landscape and functional exploration of kidney cancer predisposition in cross-ancestral populations.Semantic proximity Read ↗

Dissecting shared genetic architecture between pan-cancer and aging-related traits: a genome-wide cross-trait analysis.Semantic proximity Read ↗

Genome-wide mutation profiling and related risk signature for prognosis of papillary renal cell carcinomaSemantic proximity Read ↗

Allelic imbalance reveals widespread germline-somatic regulatory differences and prioritizes risk loci in Renal Cell CarcinomaSemantic proximity Read ↗

A pan-cancer analysis of the role of WDFY2 in human tumors.Semantic proximity Read ↗

Identification of key genes associated with papillary thyroid microcarcinoma characteristics by integrating transcriptome sequencing and weighted gene co-expression network analysis.Semantic proximity Read ↗

Integrative analysis of prognostic long non-coding RNAs with copy number variation in bladder cancerSemantic proximity Read ↗

Comprehensive integrative profiling of upper tract urothelial carcinomas.Semantic proximity Read ↗

Assessment of SWI/SNF chromatin remodeling complex related genes as potential biomarkers and therapeutic targets in pan-cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.