Article
Association of P2Y12 G52T genetic polymorphism with recurrent thromboembolic events in stroke and myocardial infarction patients on clopidogrel therapy: a prospective observational study.
Scientific reports - 1 Apr 2026
Baiju Anite, Riyas M, Rajalakshmi S, Ratan Chameli, Babu Anjana, Rapheal Mariya, David Sachin, Rani P T Karthika, Jeengar Manish Kumar, Chandran Divyasree, Sreekumar Sarath, Roshni P R, Haque Shafiul, Thunga Girish P, Rajalakshmi R, Kamalasanan Kaladhar, Nambiar Vivek, Kumar R Uday
Abstract excerpt
Cerebrovascular accidents like ischemic stroke and cardiovascular diseases together serve as the cause for 17.7 million deaths, in which Indians account for one-fifth of these cases. Around 4–30% of patients taking clopidogrel have no or reduced antiplatelet response. Clopidogrel response is influenced by genetic factors as well as non-genetic factors such as obesity, hypertension, diabetes mellitus, age, gender,...
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