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Article

The association of CYP2C19 LoF alleles with adverse clinical outcomes in stroke patients taking clopidogrel: An updated meta-analysis.

Clinical and translational science - 1 Apr 2024

Biswas Mohitosh, Hossain Md Shahadat, Ahmed Rupok Tahsin, Hossain Md Sabbir, Sukasem Chonlaphat

Abstract excerpt

The aggregated risk of recurrent stroke in stroke/transient ischemic attack (TIA) patients carrying CYP2C19 LoF alleles who take clopidogrel has not been investigated recently, and the available research is limited. This study aimed to perform an updated meta-analysis to assess the association between CYP2C19 LoF alleles and the risk of recurrent stroke in patients taking clopidogrel. Databases were searched for...

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Identifiers

PMID: 38581109
DOI: 10.1111/cts.13792
PMCID: PMC10997845

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