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Article

Duplex real-time qPCR assay targeting β-tubulin SNPs for detection of albendazole resistance in Haemonchus contortus.

Veterinary journal (London, England : 1997) - 1 Jun 2026

Chen Xindi, Zhang Lili, Wang Tengyu, Zhang Hao, Wang Rui, Lu Jing, Gao Wa, Wang Wenlong, Liu Chunxia

Abstract excerpt

Haemonchus contortus (H. contortus), a major gastrointestinal parasitic nematode threatening ruminants worldwide, exhibits albendazole resistance that is primarily associated with single nucleotide polymorphisms (SNPs) at specific codons of the β-tubulin isotype I gene, particularly at codons 167 (F167Y), 198 (E198A), and 200 (F200Y). Among these, mutations at codons 198 and 200 are the most frequently detected...

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PMID: 41876083
DOI: 10.1016/j.tvjl.2026.106657

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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