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Advances in the differentiation of induced pluripotent stem cells into vascular cells for the treatment of diabetic microvascular disease.

Cardiovascular diabetology - 23 Mar 2026

Wang Shuo, Zhong Hua, Wu Yupeng, Zhang Yuzhu, Sha Anxiang, Zhu Zaihan, Fang Xingyu, Bao Min, Sun Dandan

Abstract excerpt

The core pathological mechanisms of diabetic microvascular diseases, such as nephropathy, diabetic retinopathy (DR), and neuropathy, involve the dysfunction and loss of microvascular endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and pericytes (PCs). Conventional therapeutic approaches struggle to achieve structural repair and functional regeneration of damaged vessels. Induced pluripotent stem...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41872879
DOI: 10.1186/s12933-026-03141-z
PMCID: PMC13134171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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