Integrative multi-omics analysis identified FUT9 and MS4A3 as novel immune-phenotype and prognosis biomarkers for colorectal cancer and analyze the role of FUT9 in oncoimmunology.

Abstract excerpt

Colorectal cancer (CRC) is one of the most common malignant tumors worldwide. Patients with different immunophenotypes of CRC could achieve different effect of immunotherapy and yield different prognosis. With the advancement of bioinformatics, multi-omics analysis of the variations at both genomics and epigenomics levels helps a lot to provide a molecular basis for immunophenotype. Gene expression and clinical...

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