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Transient Neonatal Zinc Deficiency due to Maternal Variants in SLC30A2 : An Emerging and Atypical Candidate Gene for Maternal Carrier Screening.

American journal of medical genetics. Part A - 1 Aug 2026

Carter Christopher, Luz Danielle, Smith Emma E, Scott Stuart A, Srinivas Nivedita S, Shi Run-Zhang, Tise Christina G

Abstract excerpt

Transient neonatal zinc deficiency (TNZD) is a genetic condition that presents with dermatitis, alopecia, diarrhea, and growth faltering in breast milk-fed infants of females with a heterozygous pathogenic variant in SLC30A2, the primary zinc transporter in mammary glands. Despite being an easily treatable condition, effectively evaluating for TNZD can be challenging because the infant's genotype does not...

Topics

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Breast Feeding
Cation Transport Proteins
Exome Sequencing
Genetic Carrier Screening
Growth Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41866816
DOI: 10.1002/ajmg.a.70131

Genes

SLC30A2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Transient Neonatal Zinc Deficiency due to Maternal Variants in SLC30A2 : An Emerging and Atypical Candidate Gene for Maternal Carrier Screening.PMID 41866816Read ↗

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