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Article

A novel RHD allele (c.727 T>G) associated with reduced D antigen expression in a pregnant Chinese woman.

Vox sanguinis - 1 Jul 2026

Li Ning, Shao Linnan, Li Chunxiang, Wang Liying, Xia Yuexin, Yang Yicheng, Zhou Shihang

Abstract excerpt

BACKGROUND AND OBJECTIVES: This study aimed to characterize a novel RHD variant and to predict its potential impact on RhD antigen expression by integrating serological testing, molecular genotyping and structural modelling. MATERIALS AND METHODS: The full-length RHD gene was analysed using PacBio single-molecule real-time (SMRT) long-read sequencing. The effect of the identified variant on protein stability was...

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Identifiers

PMID: 41866238
DOI: 10.1111/vox.70258
PMCID: PMC13357001

Genes

RHD

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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