Prenatal and postnatal choline supplementation alters metabolic dysfunction-associated steatohepatitis (MASH) phenotypes in offspring exposed to maternal obesity and following a western diet into adulthood: A preliminary study.

Abstract excerpt

We previously demonstrated that prenatal choline supplementation (CS) mitigates metabolic abnormalities in mouse offspring exposed to maternal obesity. In this preliminary study we examined whether prenatal and postnatal CS can protect against the development of metabolic dysfunction-associated steatotic liver disease (MASLD) in offspring exposed to an obesogenic environment. C57BL/6 J mice were exposed to a...

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• Choline
• Diet, High-Fat
• Diet, Western
• Dietary Supplements
• Fatty Liver