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Fishing for Solutions: How Pre‐Conceptional Fish Oil Supplementation in Obese Fathers Reduces Risk of Non‐Alcoholic Fatty Liver Disease in Offspring Mice

5 Feb 2025

Abstract excerpt

Metabolic dysfunction associated fatty liver disease (MAFLD) is a chronic condition with hepatic fat accumulation. The intergenerational effect of obesity has predominantly focused on mothers, with limited studies on paternal obesity. Nutritional intervention with fish oil (FO) has beneficial effects in reducing markers of obesity. We hypothesized that supplementing obese fathers with FO before conception could...

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PMID: 39910853
DOI: 10.1002/mnfr.202400452

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