Article
Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci.
Child psychiatry and human development - 1 Feb 2023
Alfimova Margarita V, Nikitina Svetlana G, Lezheiko Tatyana V, Simashkova Nataliya V, Golimbet Vera E
Abstract excerpt
The study explored whether schizophrenia risk alleles of the DRD2 rs2514218 and ZNF804A rs1344706 polymorphisms also influenced the risk and severity of childhood-onset schizophrenia (COS) and differentiated it from autism spectrum disorders (ASD). We compared 75 children with COS to 75 children with ASD, 150 patients with adult-onset schizophrenia and 150 healthy individuals. Frequency of the DRD2 T-allele,...
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