Foxg1 regulates the development of microvillous cells in the olfactory epithelium.

doi:10.1016/j.ydbio.2026.03.009

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Article

Foxg1 regulates the development of microvillous cells in the olfactory epithelium.

Developmental biology - 1 Jun 2026

Christian Sarah K, Liwaru Laylah, Ibrahim Nusaybah, Reddy Divya, Vanderbeck Madison, Hendricks Roe C, McGraw Hillary F

Abstract excerpt

Foxg1 is a transcription factor that plays important roles in the development of the nervous and sensory systems. In the olfactory epithelium, it is known that Foxg1 is necessary for the development of subsets of olfactory sensory neurons, though its precise role remains undefined. In this study, we show that in zebrafish Foxg1a is required for the formation of microvillous olfactory sensory neurons, as well as...

Topics

Animals
Zebrafish
Olfactory Mucosa
Zebrafish Proteins
Forkhead Transcription Factors
Gene Expression Regulation, Developmental
Mutation
Microvilli
Olfactory Receptor Neurons
SOXE Transcription Factors
Stem Cells

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Identifiers

PMID: 41862116
DOI: 10.1016/j.ydbio.2026.03.009
PMCID: PMC13035338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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