Article
Case Report: Allogeneic hematopoietic stem cell transplantation in a patient with triple-allele expression at both HLA-B and HLA-C loci.
Frontiers in immunology - 1 Jan 2026
Fujita Yoshiyuki, Yoshihara Kyoko, Takahashi Daisuke, Tanaka Hidenori, Kino Yusuke, Yamagata Fuyuki, Samori Mami, Takahashi Saki, Yoshihara Satoshi
Abstract excerpt
Background: Human leukocyte antigen (HLA) matching is critical for donor selection in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Each HLA locus is normally biallelic; however, exceptionally rare cases with more than two alleles at a single locus have been reported. Case presentation: We describe a 17-year-old male with mixed phenotype acute leukemia (T/myeloid) who was found to carry three...
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