Predicting recurrence in patients with node-negative perihilar cholangiocarcinoma after an R0 resection.

doi:10.1016/j.ejso.2026.111751

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Article

Predicting recurrence in patients with node-negative perihilar cholangiocarcinoma after an R0 resection.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 May 2026

Wei Tao, Zhang Jian, Chatzipanagiotou Odysseas P, Guo Shouliang, Guglielmi Alfredo, Marques Hugo P, Aucejo Federico, Maithel Shishir K, Pulitano Carlo, Poultsides George A, Zhang Xu-Feng, Groot Koerkamp Bas, Itaru Endo, Liang Tingbo, Pawlik Timothy M

Abstract excerpt

BACKGROUND: Resection margin status and lymph node involvement are well-established predictors of recurrence following resection of perihilar cholangiocarcinoma (pCCA). However, even patients with favorable pathology including negative surgical margins (R0) and node-negative disease (N0) may experience recurrence. We sought to develop a clinically relevant tool to risk stratify patients relative to tumor...

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PMID: 41850029
DOI: 10.1016/j.ejso.2026.111751

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