Article
HIV-1 recombinants with multiple parental strains in low-prevalence, remote regions of Cameroon: evolutionary relics?
Retrovirology - 28 Apr 2010
Carr Jean K, Wolfe Nathan D, Torimiro Judith N, Tamoufe Ubald, Mpoudi-Ngole E, Eyzaguirre Lindsay, Birx Deborah L, McCutchan Francine E, Burke Donald S
Abstract excerpt
BACKGROUND: The HIV pandemic disseminated globally from Central West Africa, beginning in the second half of the twentieth century. To elucidate the virologic origins of the pandemic, a cross-sectional study was conducted of the genetic diversity of HIV-1 strains in villagers in 14 remote locations in Cameroon and in hospitalized and STI patients. DNA extracted from PBMC was PCR amplified from HIV(+) subjects....
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