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Article

The influence of polymorphisms in cytokine genes on pain and response to palliative radiotherapy in multiple myeloma patients: prospective observational study.

Scandinavian journal of pain - 1 Jan 2026

Rudzianskiene Milda, Inciura Arturas, Gerbutavicius Rolandas, Rudzianskas Viktoras, Ugenskiene Rasa, Paukstaitiene Renata, Dambrauskiene Ruta, Vaitiekus Domas, Kulboke Migle, Juozaityte Elona

Abstract excerpt

OBJECTIVES: The aim of this study was to assess the impact of polymorphisms in cytokine genes on pain severity and pain treatment with palliative radiotherapy. METHODS: 81 patients were enrolled. Pain severity and dose of analgesics were evaluated prior to radiotherapy and at 4, 12 and 24 weeks following treatment. The study analysed 12 gene polymorphisms of 6 cytokines (IL-6, IL-10, TNFα, IL-1α, IL-1β, IL-1RA)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin 1 Receptor Antagonist Protein

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Source

Identifiers

PMID: 41832666
DOI: 10.1515/sjpain-2025-0013

Genes

IL1RN
IL1A
IL1B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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