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Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2007

Reyes-Gibby Cielito C, Spitz Margaret, Wu Xifeng, Merriman Kelly, Etzel Carol, Bruera Eduardo, Kurzrock Razelle, Shete Sanjay

Abstract excerpt

INTRODUCTION: Cytokines, aberrantly produced by cancer cells, have recently been implicated in the severity of cancer-related pain. We explored if polymorphisms in candidate cytokine genes could explain variability in self-reported pain in lung cancer patients of all stages. METHODS: Pain, clinical, and demographic variables were assessed at presentation and before any cancer treatment in 446 Whites, 125...

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PMID: 18086782
DOI: 10.1158/1055-9965.EPI-07-0651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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