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Article

Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes.

Journal of pain and symptom management - 1 Dec 2009

Reyes-Gibby Cielito C, Shete Sanjay, Yennurajalingam Sriram, Frazier Marsha, Bruera Eduardo, Kurzrock Razelle, Crane Christopher H, Abbruzzese James, Evans Douglas, Spitz Margaret R

Abstract excerpt

We previously demonstrated that select cytokine gene polymorphisms in interleukin (IL)-8 are a significant predictor of pain and analgesia in patients with lung cancer. This study explores the role of 13 potentially functional polymorphisms in cytokine genes, including IL-1beta, IL-6, IL-8, IL-10, IL-18, tumor necrosis factor-alpha, and nuclear factor kappa-B subunit 1, in pain severity in patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19692203
DOI: 10.1016/j.jpainsymman.2009.04.019
PMCID: PMC2795073

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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