Article
Prognostic implications of genetic and transcriptomic abnormalities in MDS according to IPSS-R, IPSS-M, and the International Consensus Classification.
Blood cancer journal - 12 Mar 2026
Lee Wan-Hsuan, Hou Hsin-An, Lin Chien-Chin, Tsai Xavier Cheng-Hong, Tien Feng-Ming, Lo Min-Yen, Chang Yu-Sung, Peng Yen-Ling, Tseng Mei-Hsuan, Kuo Yuan-Yeh, Yu Shan-Chi, Liu Ming-Chih, Yao Chi-Yuan, Hsu Chia-Lang, Yuan Chang-Tsu, Yao Ming, Tien Hwei-Fang, Ko Bor-Sheng, Chou Wen-Chien
Abstract excerpt
Cytogenetic abnormalities and recurrent gene mutations are central to the biology and prognosis of myelodysplastic syndromes/neoplasms (MDS); however, the significance of patients without detectable genomic lesions remains unclear. In this retrospective analysis of 758 patients with primary MDS, the participants were stratified according to the presence of gene mutations and/or cytogenetic abnormalities....
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