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Article

Advancing the Diagnosis and Management of Genetic Cholestatic Liver Disease in Adults.

Digestive diseases and sciences - 1 Mar 2026

Nasir Ahmad Basil, Alkhouri Naim, Gish Robert, Jain Ajay K, Syn Wing-Kin

Abstract excerpt

Cholestatic liver diseases are a heterogeneous group of disorders characterized by impaired bile formation or flow, leading to bile salt accumulation and progressive liver injury. This term encompasses a broad spectrum of conditions, including genetic disorders, autoimmune biliary diseases, drug-induced liver injury, and mechanical or postsurgical biliary obstruction. Genetic testing has become essential in...

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PMID: 41066043
DOI: 10.1007/s10620-025-09431-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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