Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical Implications

26 Jul 2018

Abstract excerpt

Cholestasis is characterised by impaired bile secretion and accumulation of bile salts in the organism. Hereditary cholestasis is a heterogeneous group of rare autosomal recessive liver disorders, which are characterised by intrahepatic cholestasis, pruritus, and jaundice and caused by defects in genes related to the secretion and transport of bile salts and lipids. Phenotypic manifestation is highly variable,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Transport and Resistance Mechanisms
Share to Hepatitis B Virus Studies
Share to Pediatric Hepatobiliary Diseases and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30148122
DOI: 10.1155/2018/2313675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New Insights in Genetic Cholestasis: From Molecular Mechanisms to Clinical ImplicationsPMID 30148122Read ↗

A Comprehensive Review of Progressive Familial Intrahepatic Cholestasis (PFIC): Genetic Disorders of Hepatocanalicular TransportersSemantic proximity Read ↗

Familial cholestasis: progressive familial intrahepatic cholestasis, benign recurrent intrahepatic cholestasis and intrahepatic cholestasis of pregnancy.Semantic proximity Read ↗

Genotypes and different clinical variants between children and adults in progressive familial intrahepatic cholestasis: a state-of-the-art reviewSemantic proximity Read ↗

Current and future therapies for inherited cholestatic liver diseases.Semantic proximity Read ↗

Genetics in Familial Intrahepatic Cholestasis: Clinical Patterns and Development of Liver and Biliary Cancers: A Review of the LiteratureSemantic proximity Read ↗

What's new in pediatric genetic cholestatic liver disease: advances in etiology, diagnostics and therapeutic approaches.Semantic proximity Read ↗

Cholestatic liver disease.Semantic proximity Read ↗

Progressive familial intrahepatic cholestasisSemantic proximity Read ↗

Advancing the Diagnosis and Management of Genetic Cholestatic Liver Disease in Adults.Semantic proximity Read ↗

Pathology of Progressive Familial Intrahepatic Cholestasis: An update.Semantic proximity Read ↗

Progressive familial intrahepatic cholestasis and benign recurrent intrahepatic cholestasis: a review.Semantic proximity Read ↗

Inborn errors of biliary canalicular transport systems.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.