Interlaboratory exercise on the use of immunofluorescence microscopy on the blood smear for recognizing inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelets in Health and Disease.

doi:10.1016/j.jtha.2026.02.012

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Article

Interlaboratory exercise on the use of immunofluorescence microscopy on the blood smear for recognizing inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Platelets in Health and Disease.

Journal of thrombosis and haemostasis : JTH - 1 May 2026

Zaninetti Carlo, Bury Loredana, Bozzi Valeria, Zamora-Cánovas Ana, Althaus Karina, Uzun Günalp, Brown Simon, Norman Andrew, Faille Dorothée, Stepanian Alain, Kager Leo, Ohlenforst Sandra, Freyer Carmen, Semenowitsch Sina, Bonisoli Giulio Luigi, Bakchoul Tamam, Pecci Alessandro, Gresele Paolo, Thiele Thomas, Rivera Jose', Greinacher Andreas

Abstract excerpt

Immunofluorescence-based platelet phenotyping using peripheral blood smears has recently emerged as a promising method for characterizing a subgroup of inherited platelet disorders (IPD). A single-center study demonstrated its potential for accurate diagnosis of 9 disorders with characteristic platelet structural changes. The aim of this study was to evaluate the reproducibility of this approach through an...

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PMID: 41791656
DOI: 10.1016/j.jtha.2026.02.012

Genes

GATA1
GFI1B
MYH9
TUBB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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