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Article

Impact of germline genetic variation on breast cancer prognosis: a systematic review and meta-analysis.

BMC cancer - 4 Mar 2026

Gutiérrez-González Ariadna, Maciel-Cruz Eric Jonathan, Reynoso-Noverón Nancy, Mohar-Betancourt Alejandro, Villarreal-Garza Cynthia, Grimaldo Lizbeth, Trujillo-Martínez Miguel, Gómez-Flores-Ramos Liliana

Abstract excerpt

BACKGROUND: Breast cancer prognosis is the result of complex interactions between tumor biology, treatment, and host factors. While germline genetic variation is increasingly incorporated into breast cancer risk assessment and therapeutic decision-making, its role in determining prognosis remains incompletely defined. This systematic review and meta-analysis synthesizes available evidence on the association...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41781907
DOI: 10.1186/s12885-026-15808-7
PMCID: PMC13122941

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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