Mutation of Eamy_RS26425, hldE, or pgm renders Erwinia amylovora CFBP 1430 multi-phage resistant and avirulent.

doi:10.1128/aem.01523-25

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Article

Mutation of Eamy_RS26425, hldE, or pgm renders Erwinia amylovora CFBP 1430 multi-phage resistant and avirulent.

Applied and environmental microbiology - 22 Apr 2026

Knecht Leandra E, Born Yannick, Pelludat Cosima, Gayder Steven, Loessner Martin J, Fieseler Lars

Abstract excerpt

With the rise of antibiotic-resistant pathogens, bacterial infections have become an increasingly significant threat. Bacteriophages have the potential to complement the current treatment options. To ensure that phage biocontrol is efficient and long-lasting, the risk of resistance development must be minimized, and phage resistance mechanisms should be thoroughly investigated. In this study, a Tn5 transposon...

Topics

Erwinia amylovora
Bacteriophages
Bacterial Proteins
Virulence
Mutation
Plant Diseases

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Identifiers

PMID: 41778772
DOI: 10.1128/aem.01523-25
PMCID: PMC13101476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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