Multi-Omic Analysis of Bacteriophage-Insensitive Mutants Reveals a Putative Role for the Rcs Two-Component Phosphorelay System in Phage Resistance Development in Erwinia amylovora.

Abstract excerpt

Phage therapy has garnered significant attention due to the rise of life-threatening multidrug-resistant pathogenic bacteria and the growing awareness of the transfer of resistance genes between pathogens. Considering this, phage therapy applications are being extended to target plant pathogenic bacteria, such as Erwinia amylovora, which causes fire blight in apple and pear orchards. Understanding the mechanisms...

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