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First Report of Fluconazole-Resistant Candida parapsilosis Harbouring the G458S ERG11p Substitution in a Brazilian Hospital.

Mycoses - 1 Mar 2026

Gonçalves Sarah Santos, Maifrede Simone Bravim, Yäkel Eduardo, Peçanha Pedro Massaroni, Bessa-Neto Francisco Ozório, Cayô Rodrigo, Rodrigues Anderson Messias, Muñoz Patricia, Escribano Pilar, Guinea Jesús

Abstract excerpt

BACKGROUND: Fluconazole-resistant Candida parapsilosis is a matter of concern. OBJECTIVES: To investigate fluconazole resistance among Candida parapsilosis complex isolates from patients admitted to three Brazilian hospitals, and to characterise resistance mechanisms and clonal relatedness. PATIENTS/METHODS: A total of 76 C. parapsilosis complex isolates were collected from 60 patients hospitalised at three...

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Identifiers

PMID: 41778526
DOI: 10.1111/myc.70160
PMCID: PMC12958792

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