Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution.

doi:10.1128/aac.00710-22

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Evidence of Fluconazole-Resistant Candida parapsilosis Genotypes Spreading across Hospitals Located in Madrid, Spain and Harboring the Y132F ERG11p Substitution.

Antimicrobial agents and chemotherapy - 16 Aug 2022

Díaz-García Judith, Gómez Ana, Alcalá Luis, Reigadas Elena, Sánchez-Carrillo Carlos, Pérez-Ayala Ana, Gómez-García de la Pedrosa Elia, González-Romo Fernando, Merino-Amador Paloma, Cuétara María Soledad, García-Esteban Coral, Quiles-Melero Inmaculada, Zurita Nelly Daniela, Muñoz-Algarra María, Sánchez-Romero Isabel, Durán-Valle María Teresa, Sánchez-García Aída, Alcoceba Eva, Muñoz Patricia, Escribano Pilar, Guinea Jesús

Abstract excerpt

We have been monitoring the antifungal resistance in Candida parapsilosis isolates collected from inpatients at Madrid metropolitan area hospitals for the last 3 years. The study aimed to elucidate the presence of fluconazole-resistant C. parapsilosis genotypes in Madrid. From January 2019 to December 2021, a total of 354 C. parapsilosis isolates (n = 346 patients) from blood (76.6%) or intraabdominal samples...

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PMID: 35852369
DOI: 10.1128/aac.00710-22
PMCID: PMC9380585

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