Evaluating resolution requirements for subtle caenorhabditis elegans strain discrimination using classical descriptors and CNN-transformer models.

Abstract excerpt

Accurately distinguishing subtle phenotypic differences between Caenorhabditis elegans strains remains a major challenge in functional genetics and behavioural studies. Here, we evaluate how image resolution affects strain discrimination using an automated Multiview system combining macroscopic plate-level imaging with high-resolution microscopic single-worm recordings. Three strains were analysed: wild-type N2,...

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