Article
Involvement of SPARC and MMP-3 in the pathogenesis of human pterygium.
Investigative ophthalmology & visual science - 2 Feb 2012
Seet Li-Fong, Tong Louis, Su Roseline, Wong Tina T
Abstract excerpt
PURPOSE: To investigate the expression of SPARC and matrix metalloproteinases (MMPs) in normal conjunctiva and pterygium tissues. METHODS: This study involved paired control or uninvolved conjunctiva and pterygium tissue from 21 patients. Quantitative real-time PCR was performed to assess SPARC and MMP mRNA expression, whereas Western blot analysis was performed to assess SPARC protein levels in normal...
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