Nanoyeast-based impedimetric biosensor with mutated single chain antigen-binding fragment anchoring for SARS-CoV-2 detection.

doi:10.1007/s10544-026-00799-w

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Nanoyeast-based impedimetric biosensor with mutated single chain antigen-binding fragment anchoring for SARS-CoV-2 detection.

Biomedical microdevices - 2 Mar 2026

Hensel Rafael Cintra, Materón Elsa Maria, Macedo Anna Julia Graboschi, Raimundo Breno Vilas Boas, Kadowaki Marco Antonio Seiki, Fuentes Deivys Leandro Portuondo, Tavares Junior Alberto Gomes, de Aquino Penteado Letícia, Zanelli Cleslei Fernando, de Azevedo Ricardo Bentes, Chorilli Marlus, de Medeiros Alexandra Ivo, Carrilho Emanuel, Oliveira Osvaldo N, Valentini Sandro Roberto, Souza-Moreira Tatiana Maria

Abstract excerpt

Impedimetric biosensors are useful for pathogen detection as they combine electrical impedance spectroscopy with the specificity of immunological reactions. These devices can be engineered to detect minute changes in electrical impedance caused by interactions between immobilized recognition elements and target antigens in a sample. They are advantageous in allowing for label-free and real-time detection, with...

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PMID: 41770397
DOI: 10.1007/s10544-026-00799-w
PMCID: PMC12953393

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