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Article

Integrating Genomic and Nongenomic Data to Stratify the Risk of Contralateral Breast Cancer After Radiation Therapy.

International journal of radiation oncology, biology, physics - 1 Aug 2026

Lee Sangkyu, Shu Xiang, Derkach Andriy, Reiner Anne S, Liang Xiaolin, Woods Meghan, Concannon Patrick, Lynch Charles F, Malone Kathleen E, Knight Julia A, John Esther M, Deasy Joseph O, Bernstein Jonine L, Oh Jung Hun

Abstract excerpt

PURPOSE: Women treated with radiation therapy (RT) for breast cancer have an increased risk of developing radiation-associated contralateral breast cancer (CBC). Predicting CBC events is challenging because of the complex interplay of genomic, treatment, personal, and clinical factors. This study investigated computational methods that integrate genome-wide single-nucleotide polymorphisms and nongenomic data to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41763494
DOI: 10.1016/j.ijrobp.2026.02.237
PMCID: PMC13051349

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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