Article
Genetic Mutations and Mitochondrial Redox Signaling as Modulating Factors in Hypertrophic Cardiomyopathy: A Scoping Review.
International journal of molecular sciences - 28 May 2024
Menezes Junior Antonio da Silva, França-E-Silva Ana Luísa Guedes de, Oliveira Henrique Lima de, Lima Khissya Beatryz Alves de, Porto Iane de Oliveira Pires, Pedroso Thays Millena Alves, Silva Daniela de Melo E, Freitas Aguinaldo F
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is a heart condition characterized by cellular and metabolic dysfunction, with mitochondrial dysfunction playing a crucial role. Although the direct relationship between genetic mutations and mitochondrial dysfunction remains unclear, targeting mitochondrial dysfunction presents promising opportunities for treatment, as there are currently no effective treatments available for...
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