Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Application of Probabilistic Genotyping Software to Paternity Cases Involving Low-Template DNA.

Genes - 1 Feb 2026

Riem Alessia, Chierto Elena, Bertolotto Federica, Parnigoni Marco, Aneli Serena, Robino Carlo

Abstract excerpt

Background: Interpreting short tandem repeat (STR) profiles from low-template DNA (LT-DNA) requires consideration of the stochastic phenomena that can affect the reliability of genotypes. Although several probabilistic genotyping tools have been developed to model such uncertainties, most have only been used for direct comparisons between persons of interest and crime scene samples. Their application to kinship...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA
Share to DNA Fingerprinting
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotyping Techniques

Share to Microsatellite Repeats

Share to Paternity

Share to Pedigree

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 41751571
DOI: 10.3390/genes17020187
PMCID: PMC12940192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Application of Probabilistic Genotyping Software to Paternity Cases Involving Low-Template DNA.PMID 41751571Read ↗

The Probabilistic Genotyping Software STRmix: Utility and Evidence for its Validity.Semantic proximity Read ↗

Interpretation and statistical evaluation of multilocus DNA fingerprints in paternity and relationship testing.Semantic proximity Read ↗

Probabilistic genotyping of non-human DNA mixtures: Using MaSTR™ to analyze mixed canine STRs genotyped with DogFiler.Semantic proximity Read ↗

Forensic investigative genetic genealogy based on low-quality DNA whole genome sequencing data.Semantic proximity Read ↗

'Low' LRs obtained from DNA mixtures: On calibration and discrimination performance of probabilistic genotyping software.Semantic proximity Read ↗

Extended evaluation of the impact of dropout probability on likelihood ratios calculated in parent-child and full sibling analysis.Semantic proximity Read ↗

Encoding of low-quality DNA profiles as genotype probability matrices for improved profile comparisons, relatedness evaluation and database searches.Semantic proximity Read ↗

[Biostatistical interpretation of DNA paternity testing in cases of closely related alleged and biological fathers].Semantic proximity Read ↗

Combining autosomal and Y-chromosomal short tandem repeat data in paternity testing with male child: methods and application.Semantic proximity Read ↗

The risk of false inclusion of a relative in parentage testing - an in silico population study.Semantic proximity Read ↗

Uncertainty in probabilistic genotyping of low template DNA: A case study comparing STRMix™ and TrueAllele™.Semantic proximity Read ↗

Addresing complex kinship and incidental findings in MPI/DVI databases Using SNPs Panels to Strengthen Casework Reporting.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.