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Article

A Global Assessment of the Transcription-Dependent Single Nucleotide Variants Relies on the Characteristics of RNA-Sequencing Technologies.

Biomolecules - 29 Jan 2026

Zhang Xia, Liu Jiawei, Zhu Yabing, Hou Guixue, Bai Mingzhou, Li Yuxin, Cui Wenbo, Liu Siqi

Abstract excerpt

Single nucleotide variants (SNVs) are crucial in cancer occurrence and development. SNVs at the transcriptomic level generally come from genomic variants (g-tSNVs) and RNA editing (e-tSNVs). The types and quantities of e-tSNVs remain a subject of debate due to a relatively poor understanding of RNA editing processes. Herein, we developed TSCS (Transcript SNVs Classifier relying on complementary sequencings), a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41750281
DOI: 10.3390/biom16020211
PMCID: PMC12937670

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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