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Article

The discrepancy among single nucleotide variants detected by DNA and RNA high throughput sequencing data.

BMC genomics - 3 Oct 2017

Guo Yan, Zhao Shilin, Sheng Quanhu, Samuels David C, Shyr Yu

Abstract excerpt

BACKGROUND: High throughput sequencing technology enables the both the human genome and transcriptome to be screened at the single nucleotide resolution. Tools have been developed to infer single nucleotide variants (SNVs) from both DNA and RNA sequencing data. To evaluate how much difference can be expected between DNA and RNA sequencing data, and among tissue sources, we designed a study to examine the single...

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Share to Databases, Nucleic Acid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Share to Sequence Analysis, DNA

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Identifiers

PMID: 28984205
DOI: 10.1186/s12864-017-4022-x
PMCID: PMC5629567

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