Article
Resistance variation and bacterial interactions shape adaptation of a genetically diverse pathogen population to antibiotic therapy.
The ISME journal - 14 Jan 2026
Batra Aditi, Tueffers Leif, Haas Kira, Loeblein Tabea, Botelho João, Habig Michael, Schuetz Daniel, Sakalyte Gabija, Buchholz Florian, Berríos-Caro Ernesto, Uecker Hildegard, Unterweger Daniel, Schulenburg Hinrich
Abstract excerpt
Antimicrobial resistance (AMR) poses a major threat to global human health. The emergence and spread of AMR is usually studied for single pathogen lineages. Therefore, we currently have only limited knowledge on the causes and dynamics of resistance evolution in polymicrobial or multistrain infections that involve different pathogen species or strains, respectively, even though these kinds of infections are...
Topics
- Anti-Bacterial Agents
- Pseudomonas aeruginosa
- Drug Resistance, Bacterial
- Humans
- Genetic Variation
- Adaptation, Physiological
- Pseudomonas Infections
- Evolution, Molecular