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Article

Role of uridine phosphorylase 1 in cancer: A comprehensive pan-cancer analysis highlighting its prognostic and therapeutic potential.

Medicine - 20 Feb 2026

Yu Shuihong, Jiang Tao

Abstract excerpt

Uridine phosphorylase 1 (UPP1) is implicated in numerous cancers, yet lacks comprehensive evaluation across cancer types. This pan-cancer study aims to elucidate UPP1's roles and establish its potential as a biomarker and therapeutic target. This study analyzes the expression, genetic alterations, DNA methylation, and prognostic significance of UPP1 across 33 cancer types using multiple cancer genomics databases....

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Topics

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Share to Biomarkers, Tumor
Share to DNA Methylation
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41731765
DOI: 10.1097/MD.0000000000047685
PMCID: PMC12928912

Genes

UPP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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