Back to search

Article

A multidimensional Pan-cancer analysis of CDKN1A identifies CDKN1A as an Immunological and Prognostic Biomarker

2024-09-04

Abstract excerpt

CDKN1A/p21 is well recognized for its role in cell cycle regulation and genomic stability. However, its functions in the Tumor microenvironment (TME) and tumor immunity are not yet fully understood. Hereby, we explored CDKN1A expression and immunological/prognostic values via various databases and analytical methods including cBioPortal, Kaplan-Meier, UCSCXenaShiny, TIMER, Single-cell RNA sequencing (scRNA-seq) an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
1cd7207d-c64f-5edd-ae3e-2478c3a6c714
DOI
10.1101/2024.09.03.610958
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A multidimensional Pan-cancer analysis of CDKN1A identifies CDKN1A as an Immunological and Prognostic BiomarkerDOI 10.1101/2024.09.03.610958
Cyclin Dependent Kinase Inhibitor 2A Genetic and Epigenetic Alterations Interfere with Several Immune Components and Predict Poor Clinical OutcomeSemantic proximity
CCND1 Amplification Contributes to Immunosuppression and Is Associated With a Poor Prognosis to Immune Checkpoint Inhibitors in Solid Tumors.Semantic proximity
An Integrative Human Pan-Cancer Analysis of Cyclin-Dependent Kinase 1 (CDK1)Semantic proximity
The cell senescence regulator p16 is a promising cancer prognostic and immune check-point inhibitor (ICI) therapy biomarkerSemantic proximity
Identifying the Role of NUDCD1 in Human Tumors from Clinical and Molecular MechanismsSemantic proximity
CCNA2 as an Immunological Biomarker Encompassing Tumor Microenvironment and Therapeutic Response in Multiple Cancer TypesSemantic proximity
Cyclin B1: A potential prognostic and immunological biomarker in pan-cancerSemantic proximity
Comprehensive analyses of cuproptosis-related gene CDKN2A on prognosis and immunologic therapy in human tumorsSemantic proximity
CDCA8, a mitosis-related gene, as a prospective pan-cancer biomarker: implications for survival prognosis and oncogenic immunologySemantic proximity
A pan-cancer analysis for the oncogenic role of cyclin-dependent kinase inhibitor 1B in human cancersSemantic proximity
Systematic pan-cancer analysis identifies cuproptosis-related gene DLAT as an immunological and prognostic biomarkerSemantic proximity
Identifying the Role of NUDCD1 in Human Tumors from Clinical and Molecular Mechanisms: A Study Based On Comprehensive Bioinformatics and Experimental ValidationSemantic proximity
Select a neighboring publication to make it the new centre.